The opportunity to use small injections of medicine to help with erectile dysfunction has evolved with several options now available. These injections work by relaxing certain muscles in the penis and widening blood vessels, which increases blood flow to the penis and helps to cause an erection much like some of the current oral medications used for this condition. There are now Tri-mix and Quad-mix preparations available that have 3-4 combined medications and are more potent.
Tri-mix is a mixture of Papverine plus two prostaglandins (Phentolamine and Alprostadil). This combination of medications work well together resulting in good erectile function for many patients. This mix uses smaller amounts of the prostaglandins, which can lead to pain in large amounts. The combination of the higher potency with less of the prostaglandins makes this a great starting injection and the most commonly prescribed.
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